Etude de l'Effet de Stimulations transcrâniennes en Courant Continu (tDCS) Sur Les Performances en dénomination Chez le Sujet Aphasique à Moins d'un an de Son Accident Vasculaire cérébral : Comparaison de 5 Configurations de Stimulation
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 5
- 试验地点
- 2
- 主要终点
- Percentage of improvement of picture naming
研究概览
简要总结
The aim of this work is to study the effect of transcranial direct current stimulation combined with naming therapy in acute and post-acute stroke comparing four bihemispheric positioning electrodes to a sham condition.
详细描述
TDCS have shown a positive effect on clinical outcome in naming treatment in aphasic subjects however some aspects as the positioning of the electrodes on the head are still unclear. That is why we compare the effects of four different positionings of the electrodes (two anterior over Broca's area and its homologue and two posterior over Wernicke's area and its homologue) to a sham stimulation in order to observe if a more important effect of one or another positioning could be found.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •man or woman of 18 years and older
- •aphasic patient following a first left hemispheric stroke
- •BDAE 3.0 aphasia score > or = to 1
- •stroke within 3 to 12 months before inclusion in the study
- •mother tongue = French
- •right handedness
- •signed informed consent
排除标准
- •history of other neurologic pathologies
- •epileptic seizure within 2 months before inclusion
- •bilingual patient (2 mother tongues)
- •history of cranial surgery
- •presence of intracerebral metallic material
- •unauthorized molecules at inclusion : sulpiride, rivastigmine, dextromethorphan, carbamazepine, flunarizine, levodopa
- •pregnant, parturient or lactating woman
结局指标
主要结局
Percentage of improvement of picture naming
时间窗: Before stimulation and immediately after stimulation
次要结局
未报告次要终点