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临床试验/NCT07811973
NCT07811973尚未招募不适用

Management of arachnoid_nerve Tethering in Trigeminal Neuralgia

Assiut University0 个研究点目标入组 23 人开始时间: 2026年8月31日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
23
主要终点
Bni (Barrow Neurological Institute) score improvement

研究概览

简要总结

This study aims to evaluate the clinical significance of arachnoid-trigeminal nerve conflict in patients with medically refractory trigeminal neuralgia without demonstrable neurovascular conflict on preoperative magnetic resonance imaging (MRI). Patients undergoing surgical exploration will be assessed clinically, radiologically, and intraoperatively for the presence and characteristics of arachnoid adhesions or tethering involving the trigeminal nerve. Endoscopic-assisted arachnoid release will be performed when appropriate. Postoperative pain outcome will be evaluated using the Barrow Neurological Institute (BNI) pain intensity score and the Visual Analog Scale (VAS). Recurrence, postoperative complications, MRI-intraoperative correlation, and potential predictors of favorable surgical outcome will also be evaluated.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age more 18
  • Failed medical treatment

排除标准

  • Vascular compression

研究组 & 干预措施

Trigeminal neuralgia

Experimental

Arachnoid nerve detethering

干预措施: Arachnoid nerve detethering (Procedure)

结局指标

主要结局

Bni (Barrow Neurological Institute) score improvement

时间窗: 2years

Pain free without medication

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Amgad Kotb

Mohamed

Assiut University

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