Management of arachnoid_nerve Tethering in Trigeminal Neuralgia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 23
- 主要终点
- Bni (Barrow Neurological Institute) score improvement
研究概览
简要总结
This study aims to evaluate the clinical significance of arachnoid-trigeminal nerve conflict in patients with medically refractory trigeminal neuralgia without demonstrable neurovascular conflict on preoperative magnetic resonance imaging (MRI). Patients undergoing surgical exploration will be assessed clinically, radiologically, and intraoperatively for the presence and characteristics of arachnoid adhesions or tethering involving the trigeminal nerve. Endoscopic-assisted arachnoid release will be performed when appropriate. Postoperative pain outcome will be evaluated using the Barrow Neurological Institute (BNI) pain intensity score and the Visual Analog Scale (VAS). Recurrence, postoperative complications, MRI-intraoperative correlation, and potential predictors of favorable surgical outcome will also be evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age more 18
- •Failed medical treatment
排除标准
- •Vascular compression
研究组 & 干预措施
Trigeminal neuralgia
Arachnoid nerve detethering
干预措施: Arachnoid nerve detethering (Procedure)
结局指标
主要结局
Bni (Barrow Neurological Institute) score improvement
时间窗: 2years
Pain free without medication
次要结局
未报告次要终点
研究者
Mohamed Amgad Kotb
Mohamed
Assiut University
