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临床试验/ACTRN12624000393550
ACTRN12624000393550尚未招募Unknown

nderstanding circulatory control in postural orthostatic tachycardia syndrome

niversity of Auckland0 个研究点目标入组 50 人开始时间: 2024年4月3日最近更新:
适应症

试验速览

阶段
Unknown
状态
尚未招募
发起方
入组人数
50

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Non-randomised trial
主要目的
Diagnosis
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 o limit(—)
性别
All

入选标准

  • Participants with a clinical diagnosis of POTS
  • Healthy volunteers with no history of POTS
  • Men and women
  • Aged 18 years and over

排除标准

  • Severe cardiac disease (e.g., coronary artery disease, heart failure, hypertension)
  • Primary / secondary autonomic dysfunction
  • Significant arrhythmias (e.g., atrial fibrillation, previous VT / significant ventricular ectopy)
  • Severe respiratory disease (e.g., chronic obstructive pulmonary disease)
  • Severe, uncontrolled type II diabetes
  • Significant renal or liver disease
  • Significant neurological disease including diabetic neuropathy
  • Current active treatment for cancer
  • Inflammatory disease
  • Infection or pyrexial illness
  • Uncontrolled thyroid disorders
  • Recent (< 3 months) ischemic stroke
  • Current smoker/vaper
  • Current pregnancy
  • Users of recreational drugs
  • Current hazardous alcohol use. Participant’s alcohol intake will be initially screened in the Health Screening Questionnaire. If alcohol intake exceeds recommended limits, then the participant will be assessed by AUDIT questionnaire for hazardous alcohol intake (score of 8 or more on AUDIT).
  • Inability to fully or appropriately provide consent (e.g., language issue, reading capability)
  • Underlying medical conditions, which in the opinion of the Investigator place the participant at unacceptably high risk for participating in the study

研究者

发起方
niversity of Auckland

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