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临床试验/CTRI/2018/05/013986
CTRI/2018/05/013986招募中4 期

Comparative evaluation of Triphala, Aloevera and Chlorhexidine mouthwash on Gingivitis: A randomized placebo-controlled clinical trial

PI1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2017年2月1日最近更新:

试验速览

阶段
4 期
状态
招募中
发起方
PI
入组人数
80
试验地点
1
主要终点
gingival index,bleeding index

研究概览

简要总结

Dental plaque is associated with the most prevalent oral diseases like dental caries and periodontal diseases. The removal of plaque is a determining component in the prevention of these diseases. The use of mechanical agents is a simple and cost effective method that has been demonstrated to be effective in control of gingivitis. Most of the individuals do not practice an acceptable standard of mechanical plaque removal due lack of dexterity in performing oral hygiene methods.

Aloe barbadensis, also known as aloevera, has the greatest medicinal value. Aloevera was regarded as the most effective for general therapeutic and medicinal uses. The parenchymal tissue makes up the inner portion of Aloe leaves and produces a clear, thin, tasteless, jelly-like material called Aloevera gel. The gel contains approximately 98.5% water, with the remaining 0.5–1% solid material consisting of a wide range of compounds including vitamins A, C and E. Vitamin B1 (thiamine), niacin, vitamin B2 (riboflavin), choline, folic acid, traces of vitamin B12 and enzymes such as acid phosphatase, alkaline phosphatase, amylase, lactic dehydrogenase and lipase. The purpose of the study is to evaluate the efficacy of the aloevera in treatment of gingivitis.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
All

入选标准

  • age groups of 18-40 years with chronic generalized gingivitis.
  • Minimum of 20 teeth in the mouth.
  • No periodontal treatment was done in last 6 months.

排除标准

  • poor oral hygiene Pregnancy and lactating women Patients on antibiotic therapy for last 1 month.

结局指标

主要结局

gingival index,bleeding index

时间窗: Baseline,15 days,30 days

次要结局

  • Plaque index(Baseline,15 days,30 days)

研究者

发起方
PI
申办方类型
Other [private dental college]

研究点 (1)

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