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临床试验/NCT02167581
NCT02167581已完成不适用

Confrontation Phenotypic (Clinical, Radiological, Histological) and Genotypic Epithelial Odontogenic Tumors Isolated or Syndromic Jaws

Assistance Publique - Hôpitaux de Paris1 个研究点 分布在 1 个国家目标入组 319 人开始时间: 2011年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
319
试验地点
1
主要终点
Phenotypic and genotypic lines connected to the epithelial odontogenic tumours

研究概览

简要总结

Systematically compare the phenotype and genotype of epithelial odontogenic tumors in children and adults with a clinical, radiographic, pathologic and molecular level.

Either:

establish an observatory of this multidisciplinary tumor establish a tumor bank annotated scale unparalleled testing pathophysiological hypotheses search for prognostic factors.

详细描述

This is an observational study with retrospective and prospective parts. In retrospective part be included the Patients followed between 1992 and January 2011.

In prospective part will follow the Patients will be included after the starting of study.

There are 2 centers :

  1. st center is in the service of Stomatology and Maxillofacial Surgery in the Pitie Salpetriere Hospital.
  2. nd center is in the service of Maxillofacial Surgery in hospital Armand Trousseau.

Number of patients include in the part retrospective :

研究设计

研究类型
Observational
观察模型
Cohort

入排标准

年龄范围
5 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Phenotypic and genotypic lines connected to the epithelial odontogenic tumours

时间窗: Month 24 from the surgery date

In particular, to define the link between the genotype PTCH1, the size of the tumor, its osteolytic character and the predictive factors of recurrence. Data collection at M6, M12, M18, M24 from the surgery date

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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