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临床试验/NCT06375356
NCT06375356已完成不适用

Stronger: Muscle Strengthening for Menopause

Stanford University2 个研究点 分布在 1 个国家目标入组 96 人开始时间: 2025年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
96
试验地点
2
主要终点
Liking of the intervention

研究概览

简要总结

Menopause is a period of time with increased risk for muscle and bone loss. Very few people strength train regularly at least 2 times per week, and commonly reported barriers include inadequate time and resources, worries of safety, inadequate knowledge base of what moves to do and how to do them. Menopause-aged women may report unique barriers - or perceived facilitators - to strength training. This pilot study will develop and test the feasibility and acceptability of an at-home, band-based, expert-supported strength training intervention.

详细描述

Women are at particular risk for low muscle mass as they age, because menopause causes a dramatic reduction in circulating estrogen, which accelerates muscle decline. Preserving muscle is one of the single most important factors to maintaining lifelong independence, with bone, metabolic, cardiovascular, and cognitive health benefits. The most critical behavior for growing and preserving muscle is resistance training, and conservative estimates indicate 4 in 5 US adults do not engage in any resistance training. Commonly cited barriers for women include gender-based stigmas, discouragement, negative comments, poor knowledge of how to do resistance training, poor gym accessibility, and difficulty balancing work and family life. Finally, many menopause practitioners note that with bodyweight as a large concern, many women decrease calorie intake and increase cardiovascular (not resistance) training, further compounding muscle loss. This proposed intervention study aims to develop and pilot a muscle health building intervention with and for menopausal women.

Broadly, the investigators will identify the adherence, feasibility, acceptability, and preliminary changes of a resistance training intervention for menopausal women. The investigators will pilot the 3-month "Stronger" intervention, utilizing a protocol co-designed from focus groups. We will recruit women with menopause and randomize them into one of 2 groups: 1) single-session strength training (Stronger); or 2) "Stronger snacks," the same exercises as the single-session training but broken into single-set snack sizes that are performed throughout the week. The investigators hypothesize that the strength snacks will have the highest adherence and be the most behaviorally accessible and acceptable, but post-study interviews will also help us identify motivational differences.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
35 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • one year of no periods or categorized as menopause
  • female at birth
  • English speaking

排除标准

  • unable to perform strength training movements
  • currently performing regular strength training activities or exercise

研究组 & 干预措施

Shorter Resistance Training: Stronger Snacks

Experimental

Home-based strength training exercises would be broken up into shorter segments throughout the day or week (e.g. a "snack" might be 3 sets of body-weight or band-based squats).

干预措施: Resistance Training (Behavioral)

Single Session Resistance Training: Stronger Sessions

Experimental

Home-based strength training exercises would be broken up into 3 weekly sessions throughout the week.

干预措施: Resistance Training (Behavioral)

结局指标

主要结局

Liking of the intervention

时间窗: 3 month

Liking is measured using a 5-point Likert scale from not at all (1) to extremely (5) at the end of the intervention as a measure of acceptability of the intervention.

number of strength exercises the participant logged over the intervention

时间窗: Total at the end of 3 months

The total number of strength exercises the participant logs is a measure of adherence to the intervention.

次要结局

  • Number of participants completing post 3 month measure / those randomized and consented(3 months)
  • Change in total seconds a participant can remain in a wall sit(Change from baseline to 3 months)
  • Change in number of full body weight squats in 60 seconds(Change from baseline to 3 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Marily Ann Oppezzo

Instructor, Med/Stanford Prevention Research Center

Stanford University

研究点 (2)

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