Medical Records Investigation of Whether Perioperative Dexmedetomidine Will Reduce the Duration of Mechanical Ventilation or Hospital Length of Stay in Patients Undergoing Minimally Invasive Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 81
- 试验地点
- 1
- 主要终点
- ICU and hospital length of stay
研究概览
简要总结
The concept of enhanced recovery after surgery (ERAS) is utilizing in multiple specialties widely. Early tracheal extubation is one of the components of ERAS that enhances postoperative recovery and reduces the length of stay in intensive care unit (ICU).Dexmedetomidine is a highly selective, shorter-acting α2-adrenergic receptor agonist that has both analgesic and sedativeeffects.It was associated with decreased mortality, time to extubation, and hospital length of stay in cardiac surgical patients according to previous studies.The purpose of this study was to investigate the effect of perioperative dexmedetomidine on patients undergoing minimally invasive cardiac surgery(MICS) who were early extubated after surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergone minimal invasive off-pump coronary artery bypass graft (CABG), valvular surgery or combined procedures at Far Eastern Memorial Hospital, New Taipei City, Taiwan between January 1, 2020 and August 31,
- •Age above 20 y/o
排除标准
- •Emergency surgery
- •Postoperative mechanical ventilation more than 6 hours
- •Extubated in the operating room
研究组 & 干预措施
Dex
Dexmedetomidine infusion during the perioperative period
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
ICU and hospital length of stay
时间窗: through admission, up to 1 month
postoperative mechanical ventilation duration
时间窗: up to 1 week
from the time the patient arrived at the ICU until extubation
次要结局
- postoperative complications(according to ICD 10 on medical record, daily to discharge, up to 1 month)