Investigation of Potential Retinal Toxicity Associated With Hair Dye Products Containing pPD (Para-phenylenediamine) Type Aromatic Amines
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 62
- 试验地点
- 2
- 主要终点
- % of patients with MEKAR retinopathy detected on OCT-B scan
研究概览
简要总结
Hair dye products could induce minimal forms of MEKAR retinopathies (Mitogen-activated Extracellular signal-regulated Kinase - inhibitors associated retinopathies). These minimal forms of MEKAR are likely to be underdiagnosed, since the associated visual loss is usually mild and so this condition should be considered when patients report blurred vision. The aim of the study is to analyze whether in the current population that dyes the hair, minimal forms that go unnoticed by MEKAR retinopathies can be induced.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Hair dye up to one month before the inclusion
- •Hair dye product containing aromatic amines
排除标准
- •Pregnant or lactating woman
- •Retinal pathology already known, or central serous choroiditis
结局指标
主要结局
% of patients with MEKAR retinopathy detected on OCT-B scan
时间窗: Day of inclusion, up to one month month after the last hair dye
Physiological parameter : Serous retinal detachment at the posterior pole, detected on OCT-B scan
次要结局
未报告次要终点
