Efficacy of Intravenous Dexketoprofen and Tenoxicam on Propofol Associated Injection Pain
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 118
- 试验地点
- 1
- 主要终点
- Verbal Pain Score
研究概览
简要总结
Propofol remains the most common drug for induction of general anaesthesia, although it causes considerable pain or discomfort on injection. Anesthesia providers have attempted a large number of remedies to prevent this pain on injection. Previously explored ideas include injecting propofol into larger veins, warming of the hand with hot packs, and intravenous pretreatment with numerous other medications. No studies to date have looked at the dexketoprofen and tenoxicam for the pretreatment of pain on injection caused by propofol. The investigators propose studying the use of dexketoprofen and tenoxicam for pretreatment of propofol related pain on injection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists (ASA) physical status 1 and 2
- •18 - 65 years
- •general anesthesia scheduled for elective surgery
排除标准
- •age < 18 years, > 65 years
- •pregnancy
- •patients requiring a rapid sequence induction
- •refusal to participate and patients already participating in another study
- •allergy to study drugs
- •communication difficulty
- •psychiatric and neurolojic disorders
- •use of analgesics or sedative drugs within 24 hours before surgery.
- •emergency surgery
- •history of drug or alcohol abuse
- •ASA 3 and above
研究组 & 干预措施
saline
干预措施: saline (Drug)
dexketoprofen
干预措施: dexketoprofen (Drug)
tenoxicam
干预措施: tenoxicam (Drug)
结局指标
主要结局
Verbal Pain Score
时间窗: Approximately one minute following administration of propofol.
Facial Pain Score
时间窗: Approximately one minute following administration of propofol.
次要结局
未报告次要终点
研究者
özgür yağan
MD, assistant professor
T.C. ORDU ÜNİVERSİTESİ