NCT00629668Unknown不适用
Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease
适应症
试验速览
- 阶段
- 不适用
- 试验地点
- 2
- 主要终点
- cytokine gene polymorphism
研究概览
简要总结
The prognosis of Hepatitis B virus (HBV)infection varies from minimal progressive liver disease to cirrhosis or hepatocellular carcinoma (HCC).Both viral and host genetic factors contribute to disease severity. Cytokine gene polymorphism has been regarded affecting prognosis of disease. By detecting HBV genotyping and tumor necrosis factor-alpha polymorphism, this study aime to assess their effects and interaction on disease severity of HBV-related chronic liver disease and HCC.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •HBV-positive patients
排除标准
- •HBV-negative patients
结局指标
主要结局
cytokine gene polymorphism
时间窗: years
次要结局
- cytokine gene polymorohism on severity of disease(years)
研究者
研究点 (2)
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