NCT05695118进行中（未招募）不适用
Analysis of the Prognostic Correlation Between Body Composition Analysis and Fatty Liver Progression in Patients With Fatty Liver Using Low-dose CT
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- relationship between body composition analysis result from CT and liver fat fraction
研究概览
简要总结
This study investigates relationship between fatty liver prognosis and body composition analysis result based on non-contrast low dose CT in patients with fatty liver disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •metabolic dysfunction-associated fatty liver disease (fatty liver with overweight/obesity, or type II DM or other metabolic dysfunction)
- •or non-alcoholic fatty liver disease with liver function test abnormality
- •signed informed consent
排除标准
- •chronic hepatitis B or C
- •other disease related to fatty liver such as glycogen storage disease, lipodystrophy, familial combined hyperlipidemia, hypobetalipoproteinemia, Weber-Christian syndrome or abetalipoproteinemia
- •on medication related to hepatic steatosis (tamoxifen, steroid, valproic acid, methotrexate, amiodarone)
- •diabetes after pancreatectomy
- •history of total parenteral nutrition in 6 months
- •pregnancy or nursing mother
结局指标
主要结局
relationship between body composition analysis result from CT and liver fat fraction
时间窗: 6 month after CT acquisition
relationship between visceral fat volume fraction (obtained from CT analysis using automatic body segmentation, unitless (visceral fat fraction = visceral fat volume/total body volume)) and CAP value of fibroscan
次要结局
- ratio of appropriate non-contrast low dose abdomen CT acquisition & analysis(6 month after CT acquisition)
- relationship between body composition analysis result from CT and hepatic fibrosis(6 month after CT acquisition)
- agreement between body composition analysis result from CT and bioelectrical impedance analysis (Inbody test)(6 month after CT acquisition)
研究者
Jeong Min Lee
Professor
Seoul National University Hospital
研究点 (2)
Loading locations...
相似试验
Unknown
不适用
Variation in Body Composition on the Fate of Older Subjects During SSR HospitalizationBody Weight ChangesNCT04464278Assistance Publique - Hôpitaux de Paris360
已完成
不适用
Assessment of Fat Free Mass Index and Its Impact on Health in Children With Cystic FibrosisCystic FibrosisNCT01401439University of Arkansas24
进行中（未招募）
不适用
Predictive Effect of Abdominal Fat and Muscle Area Calculated Based on Abdominal CT on Colorectal Cancer PatientsSarcopeniaObesity and OverweightColorectal CancerNCT06614699First Affiliated Hospital of Chongqing Medical University8,000
进行中（未招募）
不适用
Predictive Effect of Abdominal Fat and Muscle Area Calculated Based on Abdominal CT on Gastric Cancer PatientsGastric CancersSarcopeniaObesity and OverweightColorectal CancerNCT06606912First Affiliated Hospital of Chongqing Medical University4,000
招募中
Unknown
Registry study on the prognosis of fatty liver patients undergoing liver stiffness measurementfatty liverJPRN-UMIN000051625Ogaki Municipal Hospital6,000