IRCT20201210049674N1招募中3 期
Comparison of the effects of omeprazole and placebo in the prevention of acute gastrointestinal events in hospitalized patients with multiple sclerosis receiving corticosteroid pulse: A Prospective randomized double-blind placebo control clinical trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 102
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years（—）
- 性别
- All
入选标准
- •Patients with recurrent types of MS between 18 and 65 years and hospitalized
- •Receive 1 gram of corticosteroid pulse daily for at least 3 days
- •Patient consent to participate in the study
排除标准
- •Presence or history of peptic ulcer disease or gastroesophageal reflux disease or inflammatory bowel disease such as colitis and Crohn's disease
- •Simultaneous administration of other drugs that cause damage to the gastrointestinal mucosa and increase the risk of ulcers and bleeding, such as oral corticosteroids, NSAIDs, anticoagulants, antiplatelets, etc
- •Receive acid-suppressing drugs such as PPIs and H2R antagonists in the last week
- •Acute or chronic renal and hepatic failure clcr<30 , child-pughscore<2
- •Pregnancy and lactation
- •Patients receiving IVIG or plasma exchange at the same time, other than a corticosteroid pulse.
研究者
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