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临床试验/NCT05514951
NCT05514951已完成不适用

Study of the Prevalence of Iron Deficiency in Elderly Patient in Hospital Environment

Vifor Pharma32 个研究点 分布在 1 个国家目标入组 888 人开始时间: 2022年11月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
888
试验地点
32
主要终点
Percentage of patients diagnosed with iron deficiency on inclusion

研究概览

简要总结

Iron deficiency is defined by insufficient tissue iron stores and anemia is the ultimate stage of iron deficiency. Anemia should never be neglected in an elderly subject because it is associated with an increase in mortality, but also with a increased morbidity in terms of complications

Apart from anemia, iron deficiency is common and constitutes a factor of poor prognosis in diseases chronic, all pathologies very frequently found in the elderly. It is the origin of the deterioration in the general condition of patients, their re-hospitalization or even the progression of their pathology.

In this context where elderly patients also present a certain number of comorbidities including the pathologies mentioned previously, it is important to better diagnose the deficiency martial in the elderly patient.

详细描述

Iron deficiency (MD) is defined by insufficient tissue iron stores. Since iron is essential for the synthesis of hemoglobin, when the iron deficiency no longer makes it possible to maintain a sufficient level of erythropoiesis, anemia appears: it is the ultimate stage of iron deficiency.

Anemia is the most common haematological pathology encountered in geriatric practice. Its prevalence, in population generally ambulatory, is between 10 and 15% after the age of 65 and is greater than 20% beyond the age of 85.

Anemia should never be neglected in an elderly subject because it is associated with an increase in mortality, but also with a increased morbidity in terms of complications heart disease, cognitive decline, frailty, hospitalizations, and impairment of quality of life. About a third of anemias elderly person is attributable to a deficiency in vitamin B9 or B12 or an iron deficiency.

Apart from anemia, iron deficiency is common and constitutes a factor of poor prognosis in diseases chronic such as heart failure, kidney failure chronic or cancer, all pathologies very frequently found in the elderly. It is the origin of the deterioration in the general condition of patients, their re-hospitalization or even the progression of their pathology.

In this context where elderly patients also present a certain number of comorbidities including the pathologies mentioned previously, it is important to better diagnose the deficiency martial in the elderly patient.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
75 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Any patient hospitalized in a geriatric unit (short geriatric stay, SSR) or seen on an outpatient basis (hospitalization day, consultation)
  • Affiliated patient or beneficiary of a social healthcare system
  • Patient having given written consent

排除标准

  • Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by court order or administration

结局指标

主要结局

Percentage of patients diagnosed with iron deficiency on inclusion

时间窗: Day 1

The diagnosis of iron deficiency will be made from the measurements of the ferritinemia and CST: Ferritinemia \< 100 µg/L and/or CST \< 20%

次要结局

未报告次要终点

研究者

发起方
Vifor Pharma
申办方类型
Industry
责任方
Sponsor

研究点 (32)

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