NCT03420430Temporarily Not Available不适用
Use of GL-ONC1 in Patients With Advanced Cancers With No Standard of Care
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- Temporarily Not Available
- 试验地点
- 1
研究概览
简要总结
GL-ONC1 expanded access is for patients who are ineligible for an ongoing GL-ONC1 clinical trial. Expanded access is intended to treat individual patients with advanced stage cancers, including blood cancer, with no standard of care options for treatment. Potential patients will be evaluated individually depending on GL-ONC1 product supply.
研究设计
- 研究类型
- Expanded Access
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of advanced cancers with no standard of care option for treatment.
- •Willing and able to provide written, signed informed consent.
- •Use of adequate contraception.
- •Negative pregnancy test.
排除标准
- •Have not recovered from severe adverse events from prior therapy.
- •Major surgery occurred within 28 days prior to treatment.
- •Known immune system disorders such as HIV, or active hepatitis B or C infection.
- •Clinically significant cardiac disease (New York Heart Association Class III or IV).
- •Have received prior therapy with an oncolytic virus of any type.
- •Be receiving antiviral agent active against vaccinia virus (e.g., cidofovir, vaccinia immunoglobulin, imatinib, ST-246).
- •Have known allergy to ovalbumin or other egg products.
- •Have clinically significant dermatological disorders (e.g., eczema, psoriasis, or any unhealed skin wounds or ulcers) as assessed by the treating physician.
研究者
研究点 (1)
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