Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease During the Covid-19 Pandemic
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Alzheimer's Disease Related Quality of Life Scale
研究概览
简要总结
Our aim has been determined to investigate the effect of physical exercise alone and in combination with cognitive exercise, on cognitive, physical function and quality of life in individuals with Alzheimer's Disease during the Covid-19 pandemic period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 65 years and older
- •Diagnosed with AD according to DSM-IV diagnostic criteria by a neurologist,
- •MOCA ≥ 13
- •Clinical Dementia Rating Scale < 2
- •Having sufficient wireless support or telephone connection where the person lives
- •Who gave consent to participate in the study
- •No history of any neurological or orthopedic injury that could prevent participation in the study and affect functional mobility.
排除标准
- •Geriatric Depression Scale score > 11
- •Various mobility restrictions, musculoskeletal disorders, (wheelchair use, etc.)
- •Clinically significant aphasia (must be able to understand the therapist's commands)
- •Significant visual or sensory impairment
- •MoCA < 13
- •Having a severe musculoskeletal disorder
- •Having paralysis
- •Impaired balance
- •The presence of severe lung and heart disease
研究组 & 干预措施
Physical exercise and computerized cognitive stimulation
Supervised Physical Exercise Program (SPEP) sessions will be performed simultaneously online together with the physiotherapist and the patient. Participants will be able to do the exercises together with their caregivers if needed.
The Computerized Cognitive Stimulation Program (CCSP) (Beynex) will be planned for 12 weeks, 5 days a week, approximately 10 minutes, for a total of 40 sessions.
Fisrtly, the use of CCSP will be demonstrated to the patients. Then, it will be given as home program. While the patients play the games in CCSP via their smartphones, their caregivers will be informed in detail about accompanying the patients if they need it. The follow-up of cognitive stimulation will be made with the person accompanying the patient over the phone.
Individuals will be evaluated by a physiotherapist who will perform the assessment at pre-treatment, post-treatment (12th week) and follow-up period (24th week).
干预措施: Physical exercise and computerized cognitive training (Other)
physical exercise
SPEP sessions will be demonstrated to individuals by a 6-year-experienced physiotherapist via videoconference (Zoom Inc.) and the exercises will be performed simultaneously online together with the physiotherapist and the patient. Participants will be able to do the exercises together with their caregivers if needed.
Individuals will be evaluated by a physiotherapist who will perform the assessment at pre-treatment, post-treatment (12th week) and follow-up period (24th week).
干预措施: Physical exercise (Other)
control
The individuals included in this group will be informed that they should continue their normal daily life activities.
Individuals will be evaluated by a physiotherapist who will perform the assessment at pre-treatment, post-treatment (12th week) and follow-up period (24th week).
结局指标
主要结局
Alzheimer's Disease Related Quality of Life Scale
时间窗: 24 weeks
This scale evaluates health-related quality of life in individuals with AD. The scale includes 40 questions in total and examines 5 quality of life domains (A-Social Interaction, B-Self Awareness, C-Affect and Mood, D- Enjoying Activities, E-Interaction with the Environment).
Arm Curl Test
时间窗: 24 weeks
The Arm Curl test is one of the subtests of the Senior fitness test and it is performed to evaluate upper extremity muscle strength
Montreal Cognitive Assessment Scale
时间窗: 24 weeks
MOCA is a short cognitive assessment method developed to detect particularly mild stages of cognitive impairment.
Berg Balance Scale
时间窗: 24 weeks
Berg Balance Scale measures static and dynamic balance in elderly individuals.
Time up and Go Test
时间窗: 24 weeks
TUG test evaluates fall risk, mobility and physical performance in the elderly
Sit to Stand Test
时间窗: 24 weeks
Sit-to-stand test will be performed on an armless chair with a height of 46 cm to determine the physical fitness level of elderly individuals
次要结局
- Katz Activities of Daily Living Scale(24 weeks)
- Lawton Instrumental Activities of Daily Living Scale(24 weeks)
- Geriatric Depression Scale (Short Form)(24 weeks)
研究者
Ebru Akbuğa Koç
Lecturer
Yeditepe University