EUCTR2020-005242-41-IT进行中（未招募）1 期
FIBRINOGEN REPLACEMENT TO PREVENT INTRACRANIAL HAEMORRHAGE IN ISCHEMIC STROKE PATIENTS AFTER THROMBOLYSIS: A PILOT PROBE RANDOMIZED CONTROLLED TRIAL - FibER
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- patients with acute ischemic stroke treated with i.v. thrombolysis (rtPA 0,9 mg/Kg, 10% in bolus and 90% in infusion in 60
- •- age >18 years
- •- critical hypofibrinogenemia post-tPA, defined as a decrease of serum fibrinogen level <200 mg/dl and/or a rate decrease
- •>50% than baseline level
- •- written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 100
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 100
排除标准
- •contraindication to rtPA treatment; patients who present symptomatic ICH during infusion of rt-PA
研究者
相似试验
已完成
3 期
Fibrinogen Replacement to Prevent Intracranial Haemorrhage in Ischemic Stroke Patients After Thrombolysis (FibER)Intracranial HemorrhagesIschemic StrokeNCT05300672Azienda Usl di Bologna207
进行中（未招募）
1 期
SUBGLOTTIC INSTILLATION OF FLURBIPROFENE TO PREVENT LARYNGEAL INFLAMMATION FOLLOWING ENDOTRACHEAL INTUBATION: PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED PILOT STUDYEUCTR2020-000886-17-ITFONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE70
已完成
不适用
Application of fibrinogen concentrate (Fibrinogen HT) to uncontrollable massive bleedingMassive bleeding during 1)Pregnancy and delivery 2)Cardiovascular surgery 3)Gastrointestinal (including hepato-biliary-pancreatic) surgeryJPRN-UMIN000022666Kagoshima University Hospital, Division of blood transfusion medicine and cell therapy26
尚未招募
不适用
eukocyte- and Platelet-Rich Fibrin for preventing Osteoradionecrosis following Tooth ExtractioRBR-8y49vfniversidade Ibirapuera
进行中（未招募）
1 期
Treatment to enhance the blood ability to clot in case of haemorrhage following child birthPostpartum blødningMedDRA version: 21.1Level: LLTClassification code 10036296Term: Postpartum haemorrhage NOSSystem Organ Class: 10036585 - Pregnancy, puerperium and perinatal conditionsMedDRA version: 21.1Level: LLTClassification code 10036294Term: Postpartum haemorrhage (primary)System Organ Class: 10036585 - Pregnancy, puerperium and perinatal conditionsMedDRA version: 21.1Level: LLTClassification code 10043454Term: Third-stage postpartum haemorrhageSystem Organ Class: 10036585 - Pregnancy, puerperium and perinatal conditionsMedDRA version: 20.1Level: PTClassification code 10036417Term: Postpartum haemorrhageSystem Organ Class: 10036585 - Pregnancy, puerperium and perinatal conditionsMedDRA version: 21.1Level: LLTClassification code 10055864Term: Other immediate postpartum haemorrhage, postpartumSystem Organ Class: 10036585 - Pregnancy, puerperium and perinatal conditionsMedDRA version: 21.1Level: PTClassification code 10043449Term: Third stage postpartum haemorrhageSystem Organ Class: 10036585 - Pregnancy, puerperium and perinatal conditionsEUCTR2009-017736-41-DKAnæstesiologisk Afd. Herlev Hospital245