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临床试验/NCT03119740
NCT03119740已完成不适用

Clinical Value of Postoperative C-reactive Protein in the Detection of Complications After Open and Laparoscopic Appendectomy

Kepler University Hospital1 个研究点 分布在 1 个国家目标入组 744 人开始时间: 2016年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
744
试验地点
1
主要终点
superficial wound infection

研究概览

简要总结

The frequency of complications after appendectomy is about 9% . The predictive value of CRP as an indicator of postoperative complications has been addressed in a small number of studies. The aim of the present retrospective analysis was to determine whether postoperative CRP levels are a reliable predictor of postoperative complications.

详细描述

Background: Acute appendicitis is a common emergency in general surgery. The frequency of complications after appendectomy is about 9% [9]. The predictive value of CRP as an indicator of postoperative complications has been addressed in a small number of studies. The aim of the present retrospective analysis was to determine whether postoperative CRP levels are a reliable predictor of postoperative complications.

Methods: This retrospective single-center cohort study comprised 744 patients who had undergone open or laparoscopic appendectomy for clinically suspected appendicitis between 1 January 2011 and 31 December 2015 at the department of general and visceral surgery, Kepler University Hospital in Linz, Austria. Demographic data, the surgical technique, postoperative complications, histopathological findings, postoperative white blood counts, and C-reactive protein levels were evaluated.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 96 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • clinically suspected appendicitis between 1 January 2011 and 31 December 2015

排除标准

  • an elective appendectomy as part of an oncological or gynecological operation tumor was found intraoperatively and required ileocecal resection or right hemicolectomy

结局指标

主要结局

superficial wound infection

时间窗: 4 weeks postoperative

superficial wound infection in open and laparoscopic appendectomy

次要结局

  • intraabdominal abscess(4 weeks postoperative)
  • ileus(4 weeks postoperative)

研究者

发起方
Kepler University Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Klugsberger Bettina

MD

Ludwig Boltzmann Institute for Operative Laparoscopy

研究点 (1)

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