NCT00461357Unknown不适用
Outcome After Renal Transplantation of a Randomized Prospective Trial in the Eurotransplant Senior Program
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 48
研究概览
简要总结
The Eurotransplant Senior Program (ESP) started in 1999 with local allocation of kidneys from deceased donors elder than 65 years to recipients elder than 65 years. The requirements for immunosuppression in this group of patients are high due to the large amount of comorbidities.
This prospective randomized trial compared the standard immunosuppressive protocol based on cyclosporine A (CyA) used at our center within the ESP, to a calcineurin inhibitor-free protocol based on sirolimus (SRL).
The aim of this study is to investigate the effect of a CNI-free therapy on the function of elderly kidneys 6 months post transplantation, measured by GFR.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Recipients of the Eurotransplant Senior Program
- •negative cytotoxic crossmatch
- •signed informed consent
排除标准
- •High sensitized recipients (PRA > 40%)
- •Non heart Beating Donor
- •Hyperlipidemia
- •Leucocytopenia (< 3000/mm3)
- •Thrombocytopenia (< 75000/mm3)
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