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临床试验/CTRI/2024/07/070030
CTRI/2024/07/070030尚未招募不适用

Study of pattern of clinical presentation and management of skin and soft tissue infection in a tertiary care rural hospital in India

Dr Deepanshu Sharma1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年7月24日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
80
试验地点
1
主要终点
clinical presentation of skin and soft tissue infection

研究概览

简要总结

Skin and Soft-tissue infections are frequent, usually mild to moderate in intensity, and

easily treated with a range of medications.Common simple SSTIs include

cellulitis, folliculitis, furuncles, carbuncles, abscesses, and trauma-related

infections that are generally easily treatable. Complicated infections extending into

and involving the underlying deep tissues include deep abscesses, decubitus ulcers,

necrotising fasciitis, Fournier gangrene, and infections from human or animal bites.

Most simple SSTIs resolve automatically.Large, complex, and painful SSTIs

require medical attention.Depending on the severity of the infection, they may need

antibiotics, suction with a syringe, incision and drainage (I/D), debridement and

drainage (D/D), amputation or even surgery may be required

Diagnosis of these infections is mostly clinical. Guidelines suggest that CBC and

wound culture should be ordered for all complicated SSTIs, and for those with sepsis

should be ordered for blood culture as well . These tests can be avoided in

uncomplicated infections.

Necrotising soft-tissue infections , or NSTIs, are extremely deadly. The degree of

organ system failure at the time of admission, age, length of infection, delayed initial

debridement, and decreased renal function are among the risk factors for death in

these cases. Treating patients with NSTI can sometimes be most challenging when it

comes to establishing the diagnosis, and early and accurate diagnosis depends onamputations are performed on diabetic patients, with chronic DFU being one of the

most common reasons for hospitalisation in this population.

Mono-microbial infections are mainly caused by haemolytic Group A Streptococcus,

Staphylococcus aureus, or clostridial species[7]. Younger people and the extremities

are affected by group A streptococcal infections, which are linked to a streptococcal

toxic shock-like syndrome.

In order to assist clinicians in determining the severity of an infection, a number of

classification methods and algorithms have been presented. Nonetheless, the majority

of clinical evaluations have been derived from either retrospective research or the

author’s personal "clinical experience," highlighting the necessity of conducting

prospective studies that include outcomes and management considerations in addition

to established severity levels.

We try to assess all the clinical circumstances related to soft-tissue infections in this

study, including the prognosis, therapy and their management outcomes.

研究设计

研究类型
Observational

入排标准

年龄范围
0.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • All patients presenting with skin and soft tissue infections of any gender.
  • Patients above 18 years of age with or without comorbidities.
  • Patient less than 18 years of age referred to the Department of surgery Patients with infection of any etiology.

排除标准

  • Patient not willing to participate in the study .
  • Patient on steroids Patients with malignancy HHH positive patients Pregnant females Patients with psychiatric illness.

结局指标

主要结局

clinical presentation of skin and soft tissue infection

时间窗: 16-34 months

次要结局

  • management outcome of skin and soft tissue infection(16-34 months)

研究者

发起方
Dr Deepanshu Sharma
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Deepanshu Sharma

Datta Meghe Institute of Higher Education and Research

研究点 (1)

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