Factors Affecting Bicarbonate Levels In Patients On Haemodialysis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Change in serum bicarbonate levels in patients on haemodialysis
研究概览
简要总结
The primary goal of this single centre observational study is to look at factors that affect serum bicarbonate levels in patients on maintenance dialysis. This will be done by collecting demographic information, relevant medical history, dialysis history, potential renal acid load from diet by recording different foods consumed over 2 days in a food diary and bicarbonate levels at 3 intervals, pre and post dialysis session 1 and pre dialysis session 2.
Bicarbonate levels are of significant interest as an indicator of metabolic acidosis in CKD dialysis patients. This study will allow us to understand the efficacy of different dialysis modalities in controlling bicarbonate levels. It will also enable us to understand the idea of individualizing dialysis for patients in terms of not using a standard concentration of dialysate for all patient undergoing dialysis in this center.
详细描述
Cross sectional study
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 years and above.
- •Ability to give informed consent.
- •End Stage Renal Disease established on maintenance dialysis for at least 3 months.
- •Patients on dialysis 3 times a week
排除标准
- •Inability to give informed consent
- •Patients with acute kidney injury
- •Patients with severe COPD
结局指标
主要结局
Change in serum bicarbonate levels in patients on haemodialysis
时间窗: 3 months
Serum bicarbonate concentration measured across two dialysis sessions (HD1 and HD2) measured as Pre HD1, Post HD2 and Pre HD2.
次要结局
- Indicators of dialysis dose(3 months)
- Dietary Acid Load(~ 3 months)
- Volume of Haemodiafiltration(3 months)