Desarrollo de un Nuevo Sistema de Mapeo de Impedancia Para la ablación de Las Arritmias Auriculares en Pacientes
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Comparative detection of atrial scar by voltage mapping
研究概览
简要总结
Precise identification of the atrial fibrosis is essential for successful catheter ablation of atrial arrhythmias in patients with atrial fibrillation. Voltage mapping of endocardial electrograms is currently used to delineate the anatomical substrate, but this is influenced by the direction of the activation wave front and is limited by the patient-specific thresholds. Mapping of local myocardial electrical impedance may overcome these limitations.
详细描述
Clinical series: Patients with atrial arrythmias undergoing catheter ablation of these will be submitted to mapping of both voltage and tissue impedance. Likewise, the accuracy of the two maps identifying the extent of the substrate will be assesssed by gadolinium imaging. The impedance system is already constructed and certified for clinical research use.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 85 years.
- •That they understand and sign the informed consent.
- •That they do not present any contraindication.- Pass the exploration and tests prior to bioimpedance measurements.
排除标准
- •Age outside the range described in the inclusion criteria.
- •Subjects who present any type of complication during the procedure.
- •Pregnancy.
结局指标
主要结局
Comparative detection of atrial scar by voltage mapping
时间窗: 30 minutes
Voltage will be measured at different sites of the atrial scar and healthy tissue.
Comparative detection of atrial scar by impedance mapping
时间窗: 30 minutes
Myocardial local impedance spectroscopy will be measured at different sites of the atrial scar and healthy tissue.
Comparative detection of atrial scar by gadolinium enhanced MR imaging
时间窗: 30 minutes
Intensity of gadolinium will be measured at different sites of the infarct scar and healthy tissue
次要结局
未报告次要终点