Response of Liver Enzymes to 12 Weeks of Resistance Band Training Program in Burned Patients.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Concentration of Alanine transaminase (ALT) and Aspartate transaminase(AST) in blood plasma.
研究概览
简要总结
Serum concentrations of alanine transaminase (ALT) and aspartate transaminase (AST) significantly increased immediately upon burn trauma and remained significantly elevated for about three years.
Resistance training has been shown to reduce the risk of insulin resistance, aminotransfer¬ase levels, dyslipidemia and impaired fasting glucose and can be beneficial for glucose-lipid metabolism.
详细描述
- Measurement procedures:
Serum blood draws will be taken by certified technicians with the participant in a seated position.
Spectrophotometry is the measurable analysis technique using electromagnetic spectra. It deals with the ranges of wavelengths such as near ultraviolet, near-infrared and visible light. A device called a spectrophotometer is used to measure the absorbance or transmittance through a liquid sample. The spectrophotometer measures a specific wavelength and it is possible to choose any wavelength in the spectrophotometer register as the double beam sends a beam through a blank reference sample and one through the sample to be measured.
Normal values that will be used for patients are 0-45 IU/l for Alanine transaminase (ALT) and 0-35 IU/l for Aspartate transaminase(AST) Measurements will be taken before the treatment (pre-treatment) and after 12 weeks (post-treatment). 2. Therapeutic procedures:
Resistance band for resistance training:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The subject selection will be according to the following criteria:
- •Age range between 20-45 years.
- •Male and female patients will participate in the study.
- •All patients have burn with BBSA about 30% to 50%.
- •All patients enrolled to the study will have their informed consent.
排除标准
- •The potential participants will be excluded if they meet one of the following criteria:
- •Cardiac diseases.
- •Burn of sole of foot.
- •Exposed hand or foot tendons.
- •Upper or Lower limb amputation.
- •History of liver diseases.
- •Body mass index (BMI=kg/cm2)<30%.
结局指标
主要结局
Concentration of Alanine transaminase (ALT) and Aspartate transaminase(AST) in blood plasma.
时间窗: Three months
Liver enzymes
次要结局
未报告次要终点
研究者
Aya Gamal Fawzy El-Sayed
Lecturer of physical therapy of surgery
Cairo University