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临床试验/NCT02579109
NCT02579109已完成不适用

Exploring Social Cognition in Autism Spectrum Disorder With Long Time Memory Task. Controlled Study on 8-13 Years Childs

Centre Hospitalier Universitaire de Nice0 个研究点目标入组 38 人开始时间: 2014年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
38
主要终点
rate of reminder after 30 minutes between the group autistic and the group witness( %)

研究概览

简要总结

Introduction:

Autism spectrum disorder is characterized by deficits in three functional domains: language and communication, social reciprocity, and the presence of restricted interests/repetitive behaviors. There's also deficits in social cognition. When having a face-to-face conversation, a listener not only hears what a speaker is saying, but also sees the articulatory gestures that accompany those sounds. Speech signals needs then a multisensory processing. Impairments in multisensory perceptual binding may be particularly relevant in ASD, given that hallmark features of the disorder include difficulties in speech, communication, and social interactions.

Objectives:

The investigator suggest that atypical multisensory processing in ASD may have an impact on speech perception and social processing.

Aims:

Methods:

This pilot study measures free recall scores in 3 lists of words presentation after 30 minutes. In the first condition (CI) words are only listening. In the second condition (CII) words are associated with a picture of a mans face. In the third condition (CIII) words are associated with a video of a man speaking. Three lists are homogeneous form words characteristics (lexical frequency, emotional valence norm, imageability). Participants were 7- to 13-year-olds typically developing children (TD) (N = 19) and ASD children (N = 19).

The investigator would create some new tools for exploring the treatment of a social information. These tools should be the closest of a ecological social interaction.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
7 Years 至 13 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Boy or girl,
  • 7 - 13 years,
  • Presenting a diagnosis DSM IV of disorder(confusion) of the autistic spectre: detected by the scale(ladder) ADI ( Autism Diagnostic Interview) or by TEENAGERS (Autism Diagnostic Observation Schedule): typical autistic. These patients do not answer the diagnosis of psychosis according to Kiddie-SADS,
  • Upper total IQ or equal to 50, examination dating less than year before the inclusion,
  • French-speaking children,
  • Signature of the informed consent by the parents(relatives) and the child,
  • Membership to the Social Security.

排除标准

  • Genetic, neurological or neurosensory pathologies,
  • Diagnosis of intrusive disorder(confusion) of the not specified development: TED our,
  • The patients will not be included who would participate in a program or a study of reeducation in the social fitnesses.

结局指标

主要结局

rate of reminder after 30 minutes between the group autistic and the group witness( %)

时间窗: 30 minutes

Comparison between the group autistic and the group witness of the difference enter the rate of reminder(abseiling) in 30 minutes of the words proposed in video and audio sequences.

次要结局

  • Difference of the scores of reminders words (%)(30 minutes)

研究者

申办方类型
Other
责任方
Sponsor

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