Immune respons after inactivated oral cholera vaccin (Dukoral) in renal transplant recipientsMucosal response in ImmunoCompromised Host (MICH) - MICH

eiden University Medical Centre0 个研究点开始时间: 2010年1月20日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•- Age = 18 years
•- Creatinin clearance = 40 ml/min
•- Stable renal function for 1 year prior to inclusion
•- Stabe immunosuppressive medication for 3 months prior to inclusion, consisting of prednisone in combination with either a calcineurine inhibitor, mycophenolate mofetil or an mTOR inhibitor
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•- A chronic disease which may influence the immune system, other than the renal transplant and accompanying immunosupressive medication
•- Chronic infection
•- Treatment for graft rejection in the year prior to inclusion
•- Prior vaccination with Dukoral or another oral cholera or ETEC vaccine.
•- Prior Vibrio cholerae infection
•- Travellers' diarrhea 6 months prior to inclusion
•- Known allergy to the vaccine or to one of the vaccine components
•- History of an anaphylactic reaction following vaccination
•- Treatment with plasma or blood products in the 3 months prior to inclusion
•- Pregnancy or breast feeding
•- Immunosuppressive medication other than prednisone, a calcineurine inhibitor, mycophenolate mofetil or an mTOR inhibitor

发起方

eiden University Medical Centre