Effect of yoga therapy on cardiac autonomic functions and oxidative stress in prehypertension subjects: a randomized controlled study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 204
- 试验地点
- 1
- 主要终点
- The addition of yoga therapy to standard lifestyle modification approaches confers additional benefits in terms of:
研究概览
简要总结
This is a randomized controlled study, the subjects with prehypertension (systolic BP 120-139 mmHg and/or diastolic BP 80-89 mmHg) will be screened in various OPDs & staffs of JIPMER, government officials and also through various screening camps in Pondicherry. After the baseline recording they will be randomized to either lifestyle modification (LSM) group or LSM + yoga group for 12 weeks. The expected primary outcome will be improved resting blood pressure, cardiovagal modulation and oxidative stress parameters. The secondary outcomes will be improved quality of life, physical and mental well-being and cardiovascular risk for next ten years.
研究设计
- 研究类型
- Interventional
- 分配方式
- Permuted block randomization, variable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
入选标准
- •SBP : 120 – 139 mmHg and / or DBP : 80 – 89 mmHg Age : 20 – 60 years Gender : both Willing to practice yoga Written informed consent.
排除标准
- •Diabetes mellitus Cardiovascular disease Autonomic failure Renal insufficiency Patients on drug treatment for prehypertension Any physical condition hindering the performance of yoga Subjects already practicing yoga Sports persons, athletes & body builders.
结局指标
主要结局
The addition of yoga therapy to standard lifestyle modification approaches confers additional benefits in terms of:
时间窗: After 12 weeks of intervention
1. Lowering resting blood pressure
时间窗: After 12 weeks of intervention
2. Increasing overall short-term HRV
时间窗: After 12 weeks of intervention
3. Indices of oxidative stress
时间窗: After 12 weeks of intervention
次要结局
- Improvement in,(1. Quality of life)