Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia in Lower Segment Caesarean Section
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 130
- 主要终点
- Incidence of hypotension
研究概览
简要总结
Spinal anesthesia for caesarean section is invariably associated with variable degree of hypotension. Hypotension that occurs may be detrimental to various organ system due to inadequate perfusion. Various methods and agents have been tried in order to address this problem. However, this calamity is far from over.
Perfusion index is one such attempt to address the problem of hypotension by predicting which group of parturient may develop hypotension. This is a type of non-invasive method of assessing the relative vascular tone with the use of pulse oximeter which calculates the ration of pulsatile versus the non-pulsatile component of the blood flow. During normal physiological changes in pregnancy, there is relative loss of vascular tone which predisposes this group of patient to sudden development of hypotension after the sympathetic block due to spinal anesthesia.
Thus, the aim of the study is to use the non-invasive perfusion index data to predict the occurrence of hypotension in a parturient so that helps us to guide fluid and other drug therapy to address the problem of hypotension.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •ASA II physical status.
- •Planned for elective LSCS
- •Gestational age >36 weeks and <41 weeks
排除标准
- •Patient's refusal.
- •Emergency LSCS.
- •Patient's with contraindications to spinal anesthesia
- •Patient with BMI >40, preeclampsia, placenta praevia.
- •Patients with comorbidities like cerebrovascular or cardiovascular disease, and gestational diabetes.
结局指标
主要结局
Incidence of hypotension
时间窗: 3 months
compare the incidence of hypotension following SAB for LSCS in parturient with or without a high perfusion index.
次要结局
- Perfusion index(3 months)
- Side-effects(3 months)
- Systolic blood pressure(3 months)
- Diastolic blood pressure(3 months)
- Mean arterial pressure(3 months)
研究者
Achyut Sharma
Dr.
Paropakar Maternity and Women's Hospital