Biomarkers and antithrombotic treatment in cervical artery dissection(TREAT-CAD) - TREAT-CAD

niversity Hospital Basel; Neurology0 个研究点目标入组 169 人开始时间: 2018年1月26日最近更新: 2021年10月8日

适应症

试验速览

暂无简介。

•1.Acute ischemic or non-ischemic symptoms within 2 weeks
•2.Verification of CAD-diagnosis (carotid and/or vertebral) by MR-techniques (at least one):
•mural hematoma or
•pseudo-aneurysm or
•long filiform stenosis or
•intimal flap or
•double lumen or
•occlusion situated more than 2 cm above the bifurcation of the carotid artery, revealing a pseudo aneurysm or a long filiform stenosis after recanalisation.
•3.Written informed consent by patient or next-to-kin
•4.24h latency period in case of thrombolysis
•5.Age > 18 years by time of inclusion (no upper age limit)
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 169
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•1. MR-contraindications (claustrophobia precluding MRI: patients agreeing to undergo MRI scanning with mild sedation may be entered into the study)
•2. Contraindications to the use of ASA or vitamin K-antagonists (see below)
•3. Pregnancy
•4. If the patient
•is allergic to Warfarin or to any of the other ingredients of this medicine
•is pregnant or may become pregnant or has had a baby in the last 48 hours
•has or has ever had any bleeding problems
•has recently had a stroke caused by bleeding in the brain
•has had surgery within the last 72 hours or is going to have surgery in the next 72 hours
•is taking non-steroidal inflammatory drugs (NSAIDs), aspirin or anti-clotting medicines (https://www.drugs.com/uk/marevan-3mg-tablets-leaflet.html)
•has a recent history of stomach or intestinal bleeding;
•has a bleeding disorder such as hemophilia; or
•has ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others. (https://www.drugs.com/aspirin.html)

发起方

niversity Hospital Basel; Neurology