Bariatric procedures and changes in incretines and gastric emptying - BIG-study

Rijnstate Ziekenhuis0 个研究点目标入组 32 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•Patients who are approaching their two years follow-up after Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) and Laparoscopic Sleeve Gastrectomy (LSG) are eligble for inclusion. The patients will be arranged in one of the following four groups according to the Reinhold*s criteria:;- Good responders (EWL > 50%) two years after RYGB
•- Bad responders (EWL < 25%) two years after RYGB
•- Good responders (EWL > 50%) two years after LSG
•- Bad responders (EWL < 25%) two years after LSG;II.
•Patients who are eligble for duodenal-jejunal bypass liner implantation. These patients have been diagnosed with type 2 and a BMI 28-45 kg/m2.

•- Binge-eating or associated eating disorder
•- Active drug or alcohol addiction
•- Gluten allergy
•- Inability to stop medication that affects the motility of the upper gastrointestinal tract (anti-cholinergic drugs, prokinetics, theophylline, calcium blocking agents, opioids)
•- Endocrine disease influencing gastric emptying (diabetes mellitus, hyper- or hypothyroidism). T2DM is not an exclusion criteria for patients receiving the DJBL because T2DM is a requirement for receiving the DJBL. Additionally, changes in GE rate will be determined 1 month after implantation. No significant changes in GE rate will be expected in this time period caused by their T2DM

发起方

Rijnstate Ziekenhuis