Characteristics and Outcomes of Odontoid Fragility Fractures in Elderly
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- bone status at the time of odontoid fracture: bone mineral density, prevalent osteoporotic fracture, vitamin D status
研究概览
简要总结
Usually, cervical spine fractures are not considered as osteoporotic fractures. However, recent studies show that odontoid fractures are the most common fractures of the cervical spine in elderly and may occur in a context of low trauma energy. Thus, the goal of this observationnal study is :
- to describe the different type of odontoid fracture and to characterize bone status in elderly patient (>65 y) who underwent odontoid fracture in a context of low trauma energy.
- To describe short and long term outcomes
详细描述
All patients over 65 y admitted for low trauma odontoid fracture will be consecutively included in the study after informed consent. The investigators will record:
- clinical risk factor of osteoporosis and health habits including accomodation
- type of fracture and characterization of the odontoid fracture on imaging (standard X ray / MRI / QCT)
- Bone status : bone mineral density on DXA, lab tests for secondary osteoporosis check-up, previous vertebral fracture on VFA or X ray
- osteoporosis managment : nutrition, vitamin D, anti-osteoporotic drugs
- treatment of the fracture : surgical / non surgical
- adverse event during hospitalization
- lenght of hospital stay
- type of discharge
Follow-up à 3 and 12 months : dead vs alive ; accomodation ; autonomy ; new fracture
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients over 65 y admitted for low traumat odontoid fracture
排除标准
- •patient < 65 y
- •traumatic odontoid fracture
结局指标
主要结局
bone status at the time of odontoid fracture: bone mineral density, prevalent osteoporotic fracture, vitamin D status
时间窗: from date of inclusion until to 3 weeks after the event. Inclusion will be proposed within 2 weeks after the fracture
clinical risk factor of osteoporosis, prevalent clinical osteoporotic fracture, bone mineral density measured by DXA, vertebral fracture assessment to detect other vertebral fracture, serum concentration in 25OHvitamin D
次要结局
- mortality(during hospitalization - 3 and 12 months after inclusion)
- morbidity(during hospitalization - 3 and 12 months after inclusion)
- loss of autonomy(discharge, 3 and 12 months)