Analysis of Salivary Minerals Level Variations in Patients With Peri-implantitis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 25
- 主要终点
- Change in levels of salivary minerals with disease progression/regression
研究概览
简要总结
Patients included in the study will be recruited after arriving at the Faculty of Dentistry of the University of Zagreb. During the clinical examination, the patient's periodontal status (bleeding during probing, and the depth of the pockets around the implant) and a control x-ray will be taken to check bone loss. Saliva sampling will occur at 3-time points, when establishing the diagnosis of periimplantitis, before the start of therapy, and at the first control after treatment.
详细描述
Work protocol Through the Department of Oral Surgery and the Department of Periodontology, patients with symptoms of peri-implantitis are admitted for a planned intervention or radiological diagnostic-therapeutic procedure within the same day. The number of patients planned for inclusion in this research on changes in the level of salivary minerals in peri-implantitis is 25.
The treatment of peri-implantitis depends on the clinical symptoms, intra- and post-therapeutic complications are not expected, and a control examination is mandatory.
Patient screening Patient selection is based on social and medical criteria. Social criteria - the patient must understand the planned procedure and the postoperative course, agree to the procedure and giving a saliva sample.
Medical criteria - at the time of departure for the planned procedure, the patient's health must be in optimally stable condition if the patient suffers from chronic diseases.
The main clinical parameters are: 1. presence of plaque, 2. presence of BOP, 3. presence of pus, 4. increased probing depth, 5. loss of alveolar bone.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed peri-implantitis
排除标准
- •uncooperative patient
- •younger then 18 years old
结局指标
主要结局
Change in levels of salivary minerals with disease progression/regression
时间窗: one year
If it is shown that the minerals of bone metabolism change according to the direction of recovery, it is possible to use salivary minerals (calcium, magnesium and phosphates) as an aid in the prognosis of the course of recovery and reduce the time needed to make a decision on the type and intensity of therapy, as well as the loss itself and implant replacement
次要结局
未报告次要终点
研究者
Ivana Sutej
associate professor
University of Zagreb