Tinnitus and Arterial Hypertension.is There Any Relationship?
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Incidence of tinnitus - have tinnitus x don't have tinnitus
研究概览
简要总结
Many authors link tinnitus to arterial hypertension. The aim of this study is to establish a possible relationship between them, analyze the severity of tinnitus related to arterial hypertension and analyze a possible influence of ototoxic drugs used to treat arterial hypertension
详细描述
Arterial hypertension has been cited as a possible tinnitus etiology. Vascular abnormalities associated with it may account for cochlear and central nervous system. However, a relationship between tinnitus and arterial hypertension has never been established. The aim of this study is to analyze this relationship, comparing groups with and without arterial hypertension and the incidence of tinnitus amongst them. Inclusion and exclusion criteria try to isolate arterial hypertension as the main etiological factor, as much as possible. Presbycusis, noise exposure, metabolical diseases and genetic factors will be ruled out. A comparison will be performed inside the arterial hypertension group between subgroups that use or not ototoxic medications, such as furosemide and beta-blockers
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 49 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age between 40 and 50
- •arterial hypertension for group 1
- •at least 5 years standing arterial hypertension
排除标准
- •chronic noise exposure
- •metabolic diseases
- •family antecedents of hearing loss (except for presbycusis)
- •pregnant women
- •use of ototoxic drugs (except for anti-hypertensives)
结局指标
主要结局
Incidence of tinnitus - have tinnitus x don't have tinnitus
时间窗: Up to 6 months
The purpose of this study is to compare tinnitus incidence between patients with and without arterial hypertension.
次要结局
- Severity of tinnitus - Tinnitus Handicap Inventory(Up to 6 months)
研究者
Ricardo Rodrigues Figueiredo
M.D, MSc
Faculdade de Medicina de Valenca
