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临床试验/NCT01333683
NCT01333683Unknown不适用

Tinnitus and Arterial Hypertension.is There Any Relationship?

Faculdade de Medicina de Valenca1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2011年4月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
100
试验地点
1
主要终点
Incidence of tinnitus - have tinnitus x don't have tinnitus

研究概览

简要总结

Many authors link tinnitus to arterial hypertension. The aim of this study is to establish a possible relationship between them, analyze the severity of tinnitus related to arterial hypertension and analyze a possible influence of ototoxic drugs used to treat arterial hypertension

详细描述

Arterial hypertension has been cited as a possible tinnitus etiology. Vascular abnormalities associated with it may account for cochlear and central nervous system. However, a relationship between tinnitus and arterial hypertension has never been established. The aim of this study is to analyze this relationship, comparing groups with and without arterial hypertension and the incidence of tinnitus amongst them. Inclusion and exclusion criteria try to isolate arterial hypertension as the main etiological factor, as much as possible. Presbycusis, noise exposure, metabolical diseases and genetic factors will be ruled out. A comparison will be performed inside the arterial hypertension group between subgroups that use or not ototoxic medications, such as furosemide and beta-blockers

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
40 Years 至 49 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • age between 40 and 50
  • arterial hypertension for group 1
  • at least 5 years standing arterial hypertension

排除标准

  • chronic noise exposure
  • metabolic diseases
  • family antecedents of hearing loss (except for presbycusis)
  • pregnant women
  • use of ototoxic drugs (except for anti-hypertensives)

结局指标

主要结局

Incidence of tinnitus - have tinnitus x don't have tinnitus

时间窗: Up to 6 months

The purpose of this study is to compare tinnitus incidence between patients with and without arterial hypertension.

次要结局

  • Severity of tinnitus - Tinnitus Handicap Inventory(Up to 6 months)

研究者

发起方
Faculdade de Medicina de Valenca
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ricardo Rodrigues Figueiredo

M.D, MSc

Faculdade de Medicina de Valenca

研究点 (1)

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