The Effects of Gait Retraining in Runners With Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Peak knee adduction moment impulse change
研究概览
简要总结
Tibiofemoral osteoarthritis (TFOA) is highly prevalent in older adults, and often causes symptoms and functional limitations. Physical activity is widely advocated in people with TFOA, and running is an easy and accessible activity that provides many benefits on general health. However, running induces high knee loads, which could potentially contribute to symptoms of runners with TFOA. Previous studies have suggested that running gait modifications can help in decreasing symptoms and knee loading in runners with knee conditions. Yet, no study has been conducted in runners with TFOA. This intervention study will investigate the effects of a 4-week running gait retraining program on symptoms and running biomechanics in runners with TFOA. We hypothesize that running modifications will decrease symptoms, improve function and reduce knee loading.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
Data will be analyzed by an assessor blinded to date of data collection for each testing session. Following data collection, a researcher not involved with data collection or analysis will re-code data timepoints to ensure that the assessor is unaware of the timepoint each datapoint was obtained.
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •TFOA of Grade 2 (mild) or 3 (moderate) on the Kellgren and Lawrence scale
- •report knee pain greater than or equal to 3/10 on a numerical pain rating scale (0-10) during most days of the previous month
- •run at least 10 km per week for a minimum of 6 months
- •declare being comfortable running on a treadmill for at least 30 minutes
排除标准
- •history of traumatic knee injury
- •neurological or inflammatory arthritic condition
- •cardiovascular or cardiopulmonary disease preventing from safely performing moderate intensity running
- •presence of any lower limb condition affecting running (other than TFOA)
- •use of any oral or injected corticosteroids or viscosupplementation in the previous six months
- •regular use of non-steroidal anti-inflammatory drugs, analgesics or knee unloading bracing devices before, during or after running
- •non-English speaking
研究组 & 干预措施
Gait retraining
Runners will be taught how to modify their running gait through multiple laboratory sessions and in-field training.
干预措施: Gait retraining (Behavioral)
结局指标
主要结局
Peak knee adduction moment impulse change
时间窗: Baseline, 4 weeks, 4 months
Validated surrogate measure of knee joint loading during movement. Expressed as Nm/kg\*sec
Knee Osteoarthritis Outcome Score (KOOS) change
时间窗: Baseline, 2 weeks, 4 weeks, 2 months, 3 months, 4 months
Validated questionnaire on symptoms and functional limitations related to knee osteoarthritis. The score is expressed in percentage (0-100), with 0 representing extreme knee problems and 100 representing no knee problems.
次要结局
- Step rate change(Baseline, 4 weeks, 4 months)
- Peak knee flexion moment impulse change(Baseline, 4 weeks, 4 months)
- Numerical pain rating scale for pain during running change(Baseline, 2 weeks, 4 weeks, 2 months, 3 months, 4 months)
研究者
Michael Hunt
Associate Professor
University of British Columbia