Mulligan Mobilization Technique Versus Neural Mobilization on Nerve Root Function in Patients With Cervical Radiculopathy: Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- F-wave parameters
研究概览
简要总结
This study will be conducted to compare the effect of sustained natural apophyseal glides (SNAGS) versus neural mobilization on clinical outcomes such as 1- nerve root function in the form of: (A) peak to peak amplitude; (B) latency; (C) F wave. 2- pain pressure threshold (PPT) and 3- Neck disability index (NDI) in patients with cervical disc (C5-C6 and/or C6-C7) herniation.
Seventy two patients from both gender with cervical disc (C 5-C 6 and/or C 6- C7) herniation with both sensory and motor nerve affections will be recruited for this study following referral from an experienced neurologist and confirmed diagnosis by MRI. The patients' age will range between 20-50 years, body mass index (BMI) from 18 to 25 kg/cm2.
The patients will be assigned randomly by permuted block to three equal groups; group (A) will receive SNAGS in addition to traditional therapy, group (B) will receive neural mobilization in addition to traditional therapy and group (C) will receive traditional therapy.
peak to peak amplitude, nerve latency and F wave will be measured by electromyography, , pressure pain threshold will be measured by commander algometer. Neck disability will be measured by Arabic neck disability index.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •seventy patients with cervical disc (C 5-C 6 and/or C 6- C7) herniation with both sensory and motor nerve affections, referred from neurologist and confirmed diagnosis by MRI
- •Both sexes.
- •Age between 20-50 years.
- •Patients with neck pain radiating down to the arm.
- •Patients with positive findings for spurling test, Upper Limb Tension Test One (ULTTO), cervical distraction test and cervical rotation test towards the symptomatic side <
- •BMI from 18 to 25 kg/cm2
- •Existed active trigger points within middle trapezius and/ or cervical region.
- •Positive Pittsburgh sleep quality index' value >10, means moderate and/ or sever difficulty.
排除标准
- •Patients experiencing primary shoulder or upper extremity problem of local origin
- •cardiovascular disorders and respiratory disorders,
- •pathological conditions involving cervical spine like vertebro basilar insufficiency and canal stenosis
- •osteophytes in cervical vertebrae
- •Patients who were undergoing treatment for neck pain with other means of physiotherapy at the time of the study
- •Cervical fractures, spinal surgery or other spinal pathologies (i.e. ankylosing spondylitis, spondylolisthesis)
- •Peripheral nerve lesions like neurotmesis and axonotmesis.
结局指标
主要结局
F-wave parameters
时间窗: Change over the course of the study, from baseline to the end of treatment program at 4 weeks
Evaluation of the spinal motoneuron excitability through the measurement of the F wave parameters
Somatosensory Evoked Potentials (SEPs) Latency and Amplitude
时间窗: Change over the course of the study, from baseline to the end of treatment program at 4 weeks
SEPs are the electrical signals generated by the nervous system in response to somatosensory stimuli. SEPs are read on the skull with electroencephalography (EEG)
Pain pressure threshold by Pressure algometer
时间窗: Change over the course of the study, from baseline to the end of treatment program at 4 weeks
An algometer will be used used to quantify pain intensity by pressure
次要结局
- Neck disability Index(Change over the course of the study, from baseline to the end of treatment program at 4 weeks)
研究者
Amany Ismail Elmetwaly Selem
Principal investigator
Cairo University