NCT00002031已完成不适用
Evaluation of the Epidermal Langerhans Cell Population in AIDS / ARC Patients by the Topical Application of a Potent Contact Allergen (1-Chloro-2,4-Dinitro-Chlorobenzene) (DNCB)
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 试验地点
- 1
研究概览
简要总结
To evaluate the effect of application of Dinitrochlorobenzene (DNCB) on the number, morphology, and antigen expression of epidermal Langerhans cells in AIDS and AIDS related complex (ARC) patients.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must have the following:
- •Stage III or IV HIV infection.
- •Provide informed consent.
排除标准
- •Co-existing Condition:
- •Patients with the following conditions or symptoms are excluded:
- •Kaposi's sarcoma lesions in the proposed treatment sites.
- •Liable to require radiation or chemotherapy during the course of the study.
- •Not likely to survive the length of the study.
- •Obvious ultra-violet-irradiated skin damage in the treatment areas and anyone with recent UV exposure or likely to have such exposure (e.g.:
- •holiday tans obtained in Hawaii, members of UV box tanning salons, etc.) Allergy to lidocaine.
- •Concurrent Medication:
- •Other Immunomodulators.
- •Concurrent Treatment:
- •Radiation.
- •Patients with the following are excluded:
- •Kaposi's sarcoma lesions in the proposed treatment sites.
- •Liable to require radiation or chemotherapy during the course of the study.
- •Not likely to survive the length of the study.
- •Obvious ultra-violet-irradiated skin damage in the treatment areas.
- •Allergy to lidocaine.
- •Prior Medication:
- •Prior DNCB therapy.
研究者
研究点 (1)
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