NL-OMON37559已完成不适用
Effects of topical corticosteroids on esophageal epithelial permeability changes and inflammation in patients with eosinophilic esophagitis - Effects of topical steroids on esophageal permeability in EoE
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •* Previous diagnosis of EoE confirmed by histopathology e.g. presence of >15 eosinophilic granulocytes per high power field (hpf) in mid-esophageal biopsies before the start of any therapy
- •* Written informed consent
- •* Age 18 * 75 years
排除标准
- •* Inability to stop topical corticosteroids
- •* Inability to stop PPI, H2-receptor antagonist or prokinetic drug for 8 weeks
- •* Use of systemic corticosteroids, leukotriene inhibitors, or monoclonal antibodies, in the two month period preceding the study
- •* Use of anticoagulants
- •* Use of NSAIDs
- •* History of peptic ulcer disease
- •* History of Barrett*s esophagus
- •* History of GI cancer
- •* History of GI tract surgery (except appendectomy)
- •* ASA class IV or V
研究者
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