ACTRN12606000152527尚未招募不适用
Effect of weight loss and ezetimibe on high-density lipoprotein (HDL)-apolipoprotein (apo) A-I and HDL apoA-II transport in obese dyslipidaemic patients
niversity of Western Australia0 个研究点目标入组 60 人开始时间: 2006年5月2日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 40 Years 至 75 Years（—）
- 性别
- All
入选标准
- •BMI <40kg/m2 will be recruited. PM will be defined by: no menstrual cycle for 1 year and FSH >30U/L, or if the subject has had a hysterectomy or surgical sterilization. The MetS will be defined by the new International Diabetes Federation (IDF) criteria: central obesity (waist circumference >80cm for women and >94cm for men) plus triglycerides =1.7mmol/L, non-HDL-cholesterol >3.4mmol/L and insulin resistance (HOMA >2.2).Exclusion: Subjects with genetic hyperlipidemia, (eg FH), LDL-cholesterol >6.5mmol/L, proteinuria, hypothyroidism, alcoholism (>30g/day), creatinaemia (>130µmol/L), hepatic dysfunction (AST or ALT >3x ULN) and major systemic illness; pre-menopause women; use of steroids or other agents that may influence lipid metabolism, cardiovascular event within past 6 months, use of hypocaloric diets, anaemia; a history of intolerance to ezetimibe.
排除标准
- •No exclusion criteria
研究者
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