Comparison Among Propofol, Alfentanil and Rocuronium as Adjunct to Sevoflurane Anesthesia for Endotracheal Intubation in Children With Frenectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- Intubating condition
研究概览
简要总结
Several methods have been demonstrated to improve intubating conditions during sevoflurane induction in children. These include opioids, propofol, and addition of neuromuscular blocking agents in pediatric patients. But the study about the comparison of these agents has been uncommon. Frenectomy is common procedure to treat ankyloglossia. It is a short procedure performed under general anesthesia. The investigators aimed to compare intubating conditions among children with propofol, alfentanil or rocuronium after sevoflurane induction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Care Provider, Investigator)
入排标准
- 年龄范围
- 1 Year 至 9 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children, 1-9 years old scheduled elective frenectomy under general anesthesia
排除标准
- •Patients with an abnormal airway, reactive airway disease, gastroesophageal reflux disease, chronic respiratory disease, or a history of an upper respiratory tract infection in the preceding 6-week period
研究组 & 干预措施
Propofol group
Intravenous administration of propofol 2 mg/kg before intubation
干预措施: administration of propofol (Drug)
Alfentanil group
Intravenous administration of alfentanil 14 μg/kg before intubation
干预措施: administration of alfentanil (Drug)
Rocuronium group
Intravenous administration of rocuronium 0.3 mg/kg before intubation
干预措施: administration of rocuronium (Drug)
结局指标
主要结局
Intubating condition
时间窗: Participants will be followed for the duration of intubation, an expected average of 1 minute.
The investigators will perform the evaluation of intubating condtion through scoring system provided by Viby-Mogensen during intubation procedure. The scoring system is consisted of excellent, good, and poor.
次要结局
未报告次要终点