NCT01422044已完成不适用
Risk Prediction in Aortic Stenosis by Cardiac Autonomic Function
Thebiosignals.com1 个研究点 分布在 1 个国家目标入组 423 人开始时间: 2009年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 423
- 试验地点
- 1
- 主要终点
- Total mortality
研究概览
简要总结
The purpose of this study is to test the prognostic value of autonomic markers in patients with aortic stenosis.
详细描述
Autonomic function will be assessed by presence of severe autonomic failure (defined by combination of abnormal heart rate turbulence and deceleration capacity).
Autonomic function will also be assessed by respiration and repolarization abnormalities.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aortic valve area ≤1.5 qcm or mean aortic gradient ≥25mmHg
排除标准
- •life expectancy <1 year due to non-cardiac causes
结局指标
主要结局
Total mortality
时间窗: 2 years
次要结局
- Cardiovascular mortality(2 years)
- Combination of cardiovascular mortality and cardiac adverse events(2 years)
- Correlation of presence of autonomic dysfunction with severity of aortic stenosis(at time of cardiac catheterization, which will be performed at an expected average of 3 days after hospital admission)
研究者
Axel Bauer
Prof. Dr. med. Axel Bauer
Thebiosignals.com
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Predicting Aortic Stenosis Progression by Measuring Serum Calcification PropensityAortic Valve SclerosisAortic Valve StenosisStenosis ProgressionValvular Heart DiseaseNCT02241109Insel Gruppe AG, University Hospital Bern200
已完成
不适用
Autonomic Function in COPD and Risk for Atrial FibrillationChronic Obstructive Pulmonary DiseaseNCT03871933Heinrich-Heine University, Duesseldorf50
Unknown
不适用
Risk Prediction in Type II Diabetics With Ischemic Heart DiseaseType-2 Diabetes MellitusIschemic Heart DiseaseNCT01422057Thebiosignals.com500
招募中
不适用
Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) StudyAortic DissectionAortic AneurysmNCT03233087Beijing Institute of Heart, Lung and Blood Vessel Diseases1,500
Unknown
不适用
Prognostic Impact of Myocardial Longitudinal Strain in Asymptomatic Aortic Stenosis: a Meta-AnalysisAortic Valve StenosisAsymptomatic ConditionsLeft Ventricular FunctionNCT02608567European Association of Cardiovascular Imaging1,000