The persisting effect of episodic exercise training in patients with chronic heart failure. - Exercise training in CHF patients/ PEP-HEART

Onze Lieve Vrouwe Gasthuis0 个研究点目标入组 135 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Inclusion criteria p 10
•* Symptomatic systolic heart failure (documented clinical signs and symptoms of heart failure) documented for more than 3 months.
•* Left ventricular ejection fraction (EF) less than 40% estimated by 2D echocardiography.
•* New York Heart Association (NYHA) class: II and III.
•* Age between 18- 80 years
•* Clinically stable with regard to symptoms and optimal medical therapy for more than 2 weeks prior to inclusion.

•exclusion criteria p 11
•* Orthopedic, peripheral vascular or neurological disease limiting the ability to exercise
•* Documented exercise-induced ischemia
•* Documented exercise-induced ventricular tachycardia
•* Poorly controlled cardiac arrhythmias
•* Significant chronic pulmonary disease limiting the ability to exercise
•* Uncontrolled hypertension
•* Abnormal blood pressure response to exercise testing (systolic blood pressure >250 mmHg or diastolic blood pressure >120 mmHg.) Or blood pressure drop of > 20mmHg during baseline exercise test.
•* Major anemia
•* Aortic valve stenose
•* Co morbidity that contraindicate exercise
•* Terminal disease
•* Patients who can*t speak/understand or read the Dutch language

发起方

Onze Lieve Vrouwe Gasthuis