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临床试验/NL-OMON40784
NL-OMON40784已完成不适用

THE EFFECT OF THORACIC EPIDURAL ANAESTHESIA WITH GENERAL ANAESTHESIA ON MEAN SYSTEMIC FILLING PRESSURE, VENOUS RETURN AND CARDIAC FUNCTION - Effect of TEA with GA on Pmsf, VR and cardiac function

eids Universitair Medisch Centrum0 个研究点目标入组 5 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
5

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • All adult patients scheduled for lung surgery under thoracic epidural and general anaesthesia

排除标准

  • * Participation in a trial on investigational drugs within 3 months prior to the study
  • * Hemodynamic instability prior to start of measurements with the systolic blood pressure decreasing more than 30% below the pre-anaesthetic value or a mean arterial pressure (MAP) < 60 mm Hg, central venous pressure (CVP) >18 mm Hg and/ or a cardiac index < 2.0 L*min-1 or dependence on high dosages of inotropic drugs after induction of general anaesthesia and before TEA.
  • * Severe arrhythmias
  • * Intra-cardiac shunts
  • * Prior diagnosis of aberrant cardiovascular anatomy
  • * Symptomatic peripheral vascular disease
  • * Severe chronic obstructive pulmonary disease (GOLD III or IV, or proven existence of lung bullae)
  • * Clinically significant aortic aneurysm
  • * Significant valvular regurgitation
  • * Use of lithium medication
  • * Diabetes requiring insulin therapy
  • * On beta blocker or calcium antagonist medication
  • * Contra-indications to epidural anaesthesia: - Increased risk of bleeding induced by medication or bleeding disorders
  • - Local infection at the insertion site
  • - Anatomic abnormalities of the spine

研究者

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