Comparison of Chlorhexidine, Green Tea, and White Tea Oral Care for the Prevention of Ventilator- Associated Pneumonia in Mechanically Ventilated Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 63
- 试验地点
- 1
- 主要终点
- ventilator associated pneumonia devolopment
研究概览
简要总结
This study was conducted to compare the effects of oral care performed using chlorhexidine (CHX), green tea, and white tea solutions on oral health, functional status, and the development of ventilator-associated pneumonia (VAP) in intensive care unit patients receiving mechanical ventilation (MV)
详细描述
This prospective controlled interventional study included 63 mechanically ventilated adult intensive care unit patients. Participants were assigned to one of three oral care groups receiving chlorhexidine (CHX), green tea, or white tea according to the study protocol. Oral health was assessed using the Bedside Oral Examination (BOE) guide on days 1, 3, and 7. The primary objective was to compare the incidence of ventilator-associated pneumonia (VAP) among the study groups. Secondary outcomes included changes in oral health status and functional oral assessment during follow-up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged over 18 years
- •With no known allergies
- •Receiving invasive mechanical ventilator support
- •With a negative endotracheal aspirate culture on the day of ICU admission
- •Within the first 24 hours of mechanical ventilator support
- •Patients whose relatives agreed to participate in the study
排除标准
- •Patients with positive endotracheal aspirate cultures within the first 48 hours of intensive care admission,
- •Patients undergoing radiotherapy or chemotherapy,
- •Patients with contraindications for oral care,
- •Patients with a platelet count below 30,000/mm³,
- •Patients who cannot be positioned appropriately,
- •Patients with agitation severe enough to prevent the procedure from being performed
研究组 & 干预措施
chlorhexidine group
Participants received oral care using chlorhexidine solution according to the study protocol.
干预措施: Clorhexidine group (Procedure)
green tea group
Participants received oral care using green tea according to the study protocol.
干预措施: Green Tea group (Procedure)
white tea group
Participants received oral care using white tea according to the study protocol.
干预措施: white tea group (Procedure)
结局指标
主要结局
ventilator associated pneumonia devolopment
时间窗: 7 days
Comparison of the incidence of ventilator-associated pneumonia among the chlorhexidine, green tea, and white tea oral care groups.
次要结局
未报告次要终点
研究者
Guleren Yartas Dumanli
Intensive care specialist
Recep Tayyip Erdogan University