NCT06493968招募中不适用
Role of Uterotonics in Reducing Intraoperative Blood Loss in Patients With Placenta Accrete Spectrum Disorders Undergoing Cesarean Hysterectomy
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Intraoperative blood loss
研究概览
简要总结
Objectives: To evaluate the effect of oxytocin in reducing intraoperative blood loss in patients with PAS disorders planned for cesarean hysterectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnancy of singleton living fetus
- •Previous one or more cesarean sections
- •Gestational age: > 32 weeks
- •The following ultrasound markers such as "loss of clear retroplacental translucency", "myometrial thinning", "abnormal lacunae", "irregular bladder wall", "utero-vesicalhypervascularity".
- •Preoperative hemoglobin more than 10 gm/dl
- •Cases with PAS that will undergoing CS Hysterectomy
排除标准
- •Maternal medical disorders e.g.: coagulation defects, cardiac diseases etc.....
- •Any known or reported hypersensitivity to the used medication.
- •All cases with spontaneous placental separation at laparotomy.
- •All patients undergoing conservative management of PAS.
- •All cases which necessitate emergency termination.
研究组 & 干预措施
Group (A)
Experimental
Patients will be given uterotonics
干预措施: oxytocin (Drug)
Group (B)
Placebo Comparator
Patients will not be given uterotonics
干预措施: placebo (Other)
结局指标
主要结局
Intraoperative blood loss
时间窗: during operation
amount of intraoperative blood loss in patients with PAS disorders undergoing cesarean hysterectomy
次要结局
- operative time(during operation)
研究者
Abdalla Mousa
Lecturer of obgyn Cairo university
Cairo University
研究点 (1)
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