Tumor Deposits in Colorectal Cancer and Its Prognostic Value in Survival and Metastasis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Patients' overall survival
研究概览
简要总结
This study aims to evaluate the tumor deposits in colorectal cancer and its prognostic value in survival and metastasis
详细描述
Tumor deposits (TDs) are defined as isolated tumor foci found in the pericolonic or perirectal fat or the adjacent mesentery (mesocolonic fat) away from the invasive margin of the tumor without evidence of residual lymphatic tissue. TDs are significantly correlated with poor prognosis after colorectal cancer surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age above 18 years old.
- •Both sexes.
- •All Colorectal cancer patients From Stage I to III Colorectal cancer with pathologically positive Tumor deposits.
排除标准
- •Patient took neoadjuvant therapy.
- •No information available on tumor deposits.
- •Colorectal cancer is not the only primary cancer.
- •Patients with incomplete information about follow-up.
研究组 & 干预措施
Therapeutic resection group
Patients with colorectal cancer underwent therapeutic resection with pathologically positive tumor deposits (TDs) to determine distant metastasis occurrence and the effect of TDs on survival.
干预措施: Therapeutic resection (Procedure)
结局指标
主要结局
Patients' overall survival
时间窗: 2 years postoperatively
Patients' overall survival (OS) is defined as from colorectal cancer (CRC) diagnosis to death.
次要结局
- Distant metastasis(2 years postoperatively)
研究者
Abdelrahman Mohamed Salah
Lecturer of General Surgery, Faculty of Medicine, Minia University, Minia, Egypt.
Minia University