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临床试验/NCT04446390
NCT04446390Unknown不适用

Evaluation of Remineralization Potential of Preventive Regimens Containing Herbal-based Compared to Fluoride-based Toothpastes in High Caries Risk Patients With Initial Carious Lesions: Randomized Clinical Trial

Cairo University2 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2021年1月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
32
试验地点
2
主要终点
Remineralization of initial carious lesions

研究概览

简要总结

This study will be conducted to assess the effect of different preventive regimens using herbal toothpaste versus fluoride toothpaste on the management of remineralization and caries risk in high caries risk patients.

详细描述

Dental caries is a major universal health problem with multiple etiological factors, so looking for economical and accurate plans for recognizing high-risk persons, and multiple risk factors to reduce the risk, in addition to caries management, using a caries risk assessment to detect the person who will develop caries, and provide them with suitable preventive and treatment regimens to disruption the disease procedure.

The treatment should evade invasive treatments and a large emphasis on prevention (using fluoride toothpaste, solutions, patient education, and so on), to achieve the aim of new dentistry (minimal intervention). The application of such a regimen to manage initial caries lesions allows the dentist to reverse initial lesions with the minimal victim of healthy dental tissues.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
15 Years 至 50 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Remineralization of initial carious lesions

时间窗: Outcomes will be evaluated at baseline, after 1 week, after 4 weeks and after 12 weeks.

changes in fluorescence of white spot lesions will be evaluated after reminerlization by using Diagnodent scoring (0-20): healthy teeth (0-14), initial carious lesions (14-20), dentinal caries (more than 20)

次要结局

  • Caries risk assessment(Outcomes will be evaluated at baseline, after 1 week, after 4 weeks and after 12 weeks.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yomna Hussin

Master degree studnet, Conservative Dentistry Department, Faculty of Dentistry, Cairo University.

Cairo University

研究点 (2)

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