Sildenafil Treatment of COPD associated Pulmonary Hypertension - Sildenafil for PH in COPD

Dept. of Pharmacology, Aarhus University0 个研究点开始时间: 2008年7月9日最近更新: 2016年9月12日

适应症

试验速览

暂无简介。

•A diagnosis of COPD-associated pulmonary hypertension by right heart catheterization.
•Stable COPD
•Able to understand and read danish
•Secure anticonception if fertile woman
•In stable treatment if treated with alfa-blockers
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Reumatological disease compromising walkning ability.
•Age > 80 years
•FEV1 < 25 % of predicted.
•Allergy to components in viagra or placebotablets.
•Treatment with nitrates or aminophyllamines.
•Severe liver insufficiency.
•Hypotension: bloodpressure < 90/50 mmHg
•Drop in blood pressure > 30/20 mm Hg or drop in peripheral saturation > 5% in relation to intake of first dose of trial medication.
•Decreased sight on one eye do to non-arteritis anterior ischaemic opticusneuropathy.
•Recent stroke or heart attack
•Certain rare inherited eye diseases (such as retinitis pigmentosa).

发起方

Dept. of Pharmacology, Aarhus University