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临床试验/NCT06999681
NCT06999681尚未招募不适用

A Prospective Study on the Association of Perioperative Echocardiographic Parameters and Other Risk Factors With Postoperative Atrial Fibrillation

National Taiwan University Hospital0 个研究点目标入组 200 人开始时间: 2025年5月26日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
200
主要终点
The occurrence of postoperative arrhythmia

研究概览

简要总结

This study aims to investigate the association between echocardiographic parameters-including preoperative cardiac echo, as well as postoperative follow-up echocardiography and other associated parameters-and the risk factors related to postoperative arrhythmia

详细描述

Postoperative atrial fibrillation (POAF), defined as newly onset atrial fibrillation occurring during hospitalization, is a common complication following cardiac surgery, affecting approximately 20-30% of patients. Studies have shown that patients who develop POAF experience longer hospital stays, incur higher medical costs, and have increased rates of stroke- and heart failure-related complications, as well as higher risks of readmission and mortality.

POAF is generally believed to result from acute perioperative triggers acting on preexisting structural abnormalities of the atria or ventricles. However, the echocardiographic predictors of POAF remain poorly understood. While previous studies have examined the association between preoperative transthoracic echocardiography (TTE)-assessed left atrial and left ventricular function and the development of POAF, the detailed relationship between intraoperative transesophageal echocardiography (TEE)-assessed atrial and ventricular function, its intraoperative changes, and POAF remains insufficiently explored.

This study aims to investigate the association between echocardiographic parameters-including preoperative TTE and TEE, as well as postoperative follow-up parameters-and the risk factors related to POAF.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients receiving cardiac surgery

排除标准

  • preoperative arrhythmia

结局指标

主要结局

The occurrence of postoperative arrhythmia

时间窗: postoperative 1 years

postoperative arrhythmia after cardiac surgery

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

National Taiwan University Clinical Trial Center

Attending anesthesiologist

National Taiwan University Hospital

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