Investigation of the Perception of Protein Fortified Foods and Beverages
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 84
- 试验地点
- 2
- 主要终点
- Saliva sample to examine change over time of protein remaining in mouth (Mucoadhesion)
研究概览
简要总结
This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
详细描述
- To investigate, by using protein fortified foods and beverages, whether mucoadhesion to the oral cavity is greater for older adults compared to younger adults and determine whether it is related to salivary flow rate.
- To determine whether protein fortification of foods and beverages causes mouthdrying and whether perception and acceptance are influenced by age and individual differences in saliva flow.
These aims will be investigated using two different models: a liquid model using whey protein and a solid model using protein fortified biscuits and cakes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Single (Participant)
盲法说明
All samples provided to the participant are labelled with 3 digit random codes
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-30 years or over 65 years
- •Self reported as healthy (no specific disease states)
排除标准
- •Cognitively impaired
- •Allergies or intolerances that include coeliac disease, lactose or gluten intolerance
- •Had oral surgery
- •Had stroke
结局指标
主要结局
Saliva sample to examine change over time of protein remaining in mouth (Mucoadhesion)
时间窗: Saliva collection at 4 timepoints post swallowing of each sample (15s, 30s, 60s, 120s) at study visits two and three, reported at 1 year.
Participants drink whey protein beverages (unheated and heated protein) then after different time points post swallowing (15 seconds to 5 minutes) expectorated saliva is collected to analyse protein for the extent of mucoadhesion)
次要结局
- Mouthdrying from whey protein(At one time point (visit 1) reported at 1 year.)
- Mouthdrying from biscuits(At one time point (visit 2) reported at 1 year.)
- Mouthdrying from cake(At one time point (visit 3) reported at 1 year.)
- Questionnaire(At one time point (visit 1) reported at 1 year.)
- Saliva Collection(Reported at 1 year (Unstimulated saliva flow taken at the start of every study visit. Stimulated saliva flow taken at the start of study visit one.))
研究者
Lisa Methven
Professor in Food and Sensory Science
University of Reading