Retrospective Analysis of Different Quadratus Lumborum Block Techniques on Recovery Quality and Analgesic Consumption in Radical Cystectomy Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Total Opioid Consumption (Morphine Milligram Equivalents) in the First 24 Hours
研究概览
简要总结
This retrospective observational study evaluates the effects of different Quadratus Lumborum Block (QLB) techniques on postoperative recovery and total opioid consumption in patients undergoing radical cystectomy under general anesthesia. The study will analyze intraoperative and postoperative patient records from October 15, 2023, to October 15, 2024, at Tekirdağ Namık Kemal University Hospital.
Patients who received anterior or posterior QLB for postoperative analgesia will be included. Data collection will involve demographic information, total opioid consumption (morphine milligram equivalents), recovery quality scores (QoR-15), postoperative pain scores (Visual Analog Scale, VAS), time to first rescue analgesic administration, frequency of rescue analgesic use, and incidence of postoperative nausea and vomiting (PONV).
The retrospective analysis will compare the two QLB techniques to determine if there is a significant difference in postoperative opioid consumption and recovery quality. Statistical methods will be used to assess pain scores over time, opioid consumption, and overall recovery quality.
详细描述
Postoperative pain management plays a crucial role in optimizing recovery after radical cystectomy, as inadequate pain control can lead to increased opioid consumption and delayed rehabilitation. This retrospective observational study examines the effects of two different Quadratus Lumborum Block (QLB) techniques-anterior and posterior approaches-on postoperative pain and opioid consumption.
The study includes patients who underwent radical cystectomy under general anesthesia at Tekirdağ Namık Kemal University Hospital between October 15, 2023, and October 15, 2024. The primary focus is to compare total opioid consumption (morphine milligram equivalents) within the first 24 hours after surgery between the two groups.
Secondary outcomes include:
- Pain scores at multiple time points (0, 2, 6, 12, 24 hours), measured using the Visual Analog Scale (VAS)
- Postoperative recovery quality scores (QoR-15)
- Time to first rescue analgesic administration
- Frequency of rescue analgesic use
- Incidence of postoperative nausea and vomiting (PONV)
Data will be collected from intraoperative and postoperative patient records. Statistical analysis will compare anterior vs. posterior QLB techniques, evaluating differences in postoperative opioid consumption, pain relief efficacy, and recovery quality (QoR-15 scores).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent radical cystectomy under general anesthesia between October 15, 2023, and October 15,
- •Patients who received anterior or posterior quadratus lumborum block (QLB) for postoperative analgesia.
- •Age: 18-65 years.
- •ASA Physical Status Classification: I-III.
- •BMI < 35 kg/m².
- •Complete medical records available for retrospective review.
排除标准
- •Patients who received a different postoperative analgesia technique (e.g., epidural, TAP block).
- •Incomplete or missing medical records.
- •Psychiatric disorders that could affect pain perception and reporting.
- •Coagulopathy or bleeding disorders.
- •Hepatic or renal failure.
- •Chronic opioid use before surgery.
- •Patients who required unplanned conversion to open surgery.
结局指标
主要结局
Total Opioid Consumption (Morphine Milligram Equivalents) in the First 24 Hours
时间窗: 0-24 hours postoperatively
The total amount of opioids (converted to morphine milligram equivalents) administered postoperatively within the first 24 hours following radical cystectomy. Continuous variable (mg of morphine equivalent)
次要结局
- Postoperative Recovery Quality (QoR-15 Score)(24 hours postoperatively)
- Pain Scores Using Visual Analog Scale (VAS) at Multiple Time Points(0, 2, 6, 12, and 24 hours postoperatively)
- Time to First Rescue Analgesic Administration(0-24 hours postoperatively)
- Incidence of Postoperative Nausea and Vomiting (PONV)(0-24 hours postoperatively)
- Frequency of Rescue Analgesic Use(0-24 hours postoperatively)
研究者
Onur Baran
Assistant Professor
Namik Kemal University