Attention Training for Learning Enhancement and Resilience Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 83
- 试验地点
- 2
- 主要终点
- Attention Measures aimed to test attention
研究概览
简要总结
Healthy aging is associated with a decline in multiple cognitive domains, as well as motor control function. The long-term consequences of cognitive and functional impairment resulting from age-related cognitive decline are well documented in the scientific and clinical literature, with significant evidence of related problems with independent functional abilities. This study aims to understand how the experimental computer program can affect cognition and attention in participants with age-related cognitive decline.
详细描述
Following consent, participants will engage in an assessment process to determine eligibility. Once eligibility is confirmed, participants will be scheduled for another assessment session to determine current level of cognitive function. This process consists of paper-pencil surveys and computerized tests. Following the assessment process, participants will engage in an Internet browser-delivered training sessions conducted on any internet-accessible computer. The computerized training sessions can be done up to 7 times a week (once a day) or at the participant's convenience (the recommended time commitment is 5 times a week). Following the completion of training, the participant's cognitive function will be re-assessed. Participation is voluntary and participants may withdraw from the study at any time.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants must be 65 years of age or older
- •Participants must have a diagnosis of age-related cognitive decline as confirmed by interview and performance on screening assessments
- •Participants must be fluent English speakers
- •Participants must have adequate visual, auditory, and motor capacity to use computerized intervention
排除标准
- •Participants with diagnosis of PTSD, depression or other psychologically diagnosable emotional disorder
- •Participants with a history of conditions that could affect thinking abilities, including brain injury, mental illness, cancer, or other neurological conditions (multiple sclerosis, seizure disorder), HIV/AIDS will be excluded
- •Participants enrolled in another concurrent research study will be excluded
- •Participants who have difficulty performing assessments or comprehending or following spoken instructions, in the judgment of the screening clinician, will be excluded
- •Participants with a current or significant past history of substance abuse will be excluded
- •Participants who show signs of suicidal ideations or behaviors will be excluded and referred for appropriate treatment
研究组 & 干预措施
Experimental Treatment
Computerized plasticity-based adaptive cognitive training requiring a total maximum of 36 treatment sessions, 4-5 times weekly, one hour each session.
干预措施: Computerized Plasticity-Based Adaptive Cognitive Training (Other)
Active Comparator
Commercially available computerized training requiring a total maximum of 36 treatment sessions, 4-5 times weekly, one hour each session.
干预措施: Commercially available computerized training (Other)
结局指标
主要结局
Attention Measures aimed to test attention
时间窗: 6 months
Measures aimed to test attention
Functional Capacity
时间窗: 6 month
Performance on directly observable functional measure
Executive Function
时间窗: 6 months
Tasks targeting inhibitory control
次要结局
- Quality of Sleep(6 months)